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KMID : 0376119940210010051
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Medical Journal of the Red Cross Hospital
1994 Volume.21 No. 1 p.51 ~ p.56
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Methacholine Bronchial Provocation Test in Children with Chronic Cough
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Abstract
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methacholine bronchial provocation test(MBPT) by modified Chai's method was done to evaluate their diagnostic value in 20 patients with chronic ough(Group 1), and 10 normal subjecvts(Group II).
@ES The results were as follows
@EN 1) In the control group, there was no decrease in FEV1 with increasing concentrations of Methacholine, and none of them showed positive response to MBPT. However in Group 1, 15 patients(75%) showed bronchial hyperreactivity with methacholine.
2) Inhalation of isoproterenol to those with positive MBPT caused significant bronchodialtion(FEV1 increase was over 20%) in 14 of 15 patients.
Therefore MBPT can be used as a valuable tool for the diagnosis and differential diagnosis of asthma in patients with chronic cough.
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